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Endophilin-B1, also known as Bax-interacting factor 1 (Bif-1, and encoded by SH3GLB1), is a multifunctional protein involved in apoptosis, autophagy and mitochondrial function. We recently described a unique neuroprotective role for neuron-specific alternatively spliced isoforms of endophilin-B1. To examine whether endophilin-B1-mediated neuroprotection could be a novel therapeutic target for A...
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Mixed (SvO2) or central (ScvO2) venous oxygen saturation is frequently used to evaluate the adequacy of global tissue oxygenation in critically ill patients. The aim of this review is to discuss the literature regarding S(c)vO2 measurement and S(c)vO2 directed therapy. Both reductions in oxygen delivery and increases in oxygen consumption without subsequent adequate rise in cardiac output can r...
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ژورنال
عنوان ژورنال: Revista Interinstitucional Artes de Educar
سال: 2019
ISSN: 2359-6856
DOI: 10.12957/riae.2019.47362